Nijagal Lab - Homepage
Amar Nijagal, MD
Associate Professor of Surgery
Division of Pediatric Surgery
UCSF Benioff Children's Hospital, San Francisco
Investigating How Immune Cells Regulate the Development and Repair of Fetal Organs
We study how immune cells may regulate the development and repair of fetal organs. Our research is currently focused on the development of the liver and bile ducts as the fetal liver is ripe with interactions between developing hepatocytes/cholangiocytes and the hematopoietic system. We are interested in identifying key relationships and interactions between immune cells and developing tissues in both the steady state and during fetal injury. Using advanced surgical techniques in mouse models, we are able to manipulate and induce injury in fetal organs. We have also employed “discovery” approaches to identify novel cell types and pathways that may serve as a link between the immune system and fetal development.
Affiliations
We are pleased to announce that Amar Nijagal, MD has been selected for the AASLD CTORA Award (American Association for the Study of Liver Diseases Foundation) for his proposal & work focused on hepatoblastoma. The award provides Dr. Nijagal with $200K of funding for 2 years and is intended to fund his research project entitled “Defining the role of tumor associated myeloid cells in pediatric hepatoblastoma.” This is a vital stepping stone for his lab & continuing science. For more information on the ASSLD CTORA Award, please visit http://www.aasldfoundation.org/
Featured News
Featured Publications
- Perinatal liver inflammation is associated with persistent elevation of CXCL10 and its canonical receptor CXCR3 on common myeloid progenitors.
2024 | PubMed - Index admission cholecystectomy for acute cholecystitis reduces 30-day readmission rates in pediatric patients.
2023 | PubMed - Neonatal Hepatic Myeloid Progenitors Expand and Propagate Liver Injury in Mice.
2023 | PubMed - Advances in the Treatment of Neonatal Biliary Disease.
2022 | PubMed - Hepatic Ly6CLo Non-Classical Monocytes Have Increased Nr4a1 (Nur77) in Murine Biliary Atresia.
2022 | PubMed
A gift to the Nijagal Lab will help us to identify novel cell types and pathways that may serve as a link between the immune system and fetal development.